Experimental Biophotonics group
Advanced light microscopy R&D areas:
- Research on novel approaches in advanced light microscopy, especially holographic and two‑photon microscopy.
- Theoretical study and numerical simulation of coherence effects in holographic microscopy, imaging in turbid media and axial localization based on coherence gating.
- Development of advanced image-processing methods for holographic reconstruction, quantitative phase imaging (QPI), as well as pattern and process recognition and/or classification.
Applications in cell biology, cancer and neuroscience research:
- Identification and classification of behavioural patterns in live cancer cells including biopsy-derived carcinoma cells using coherence-controlled holographic microscopy (CCHM).
- Development of a strategy for personalized cancer treatment based on live-cell dry-mass profiling.
- Investigation of cellular and molecular aspects of the hemodynamic response of the brain.
Applications in nanotechnology:
- Novel methods of plasmonic phenomena observation in nanostructures with CCHM.
New paper by Dr. Petr Bouchal "Geometric-phase microscopy for quantitative phase imaging of isotropic,… Read more »
New paper by Dr. Petr Bouchal "High-Resolution Quantitative Phase Imaging of Plasmonic Metasurfaces with Sensitivity… Read more »