Experimental Biophotonics group

Advanced light microscopy R&D areas:

  • Research on novel approaches in advanced light microscopy, especially holographic and two‑photon microscopy.
  • Theoretical study and numerical simulation of coherence effects in holographic microscopy, imaging in turbid media and axial localization based on coherence gating.
  • Development of advanced image-processing methods for holographic reconstruction, quantitative phase imaging (QPI), as well as pattern and process recognition and/or classification.

Applications in cell biology, cancer and neuroscience research:

  • Identification and classification of behavioural patterns in live cancer cells including biopsy-derived carcinoma cells using coherence-controlled holographic microscopy (CCHM).
  • Development of a strategy for personalized cancer treatment based on live-cell dry-mass profiling.
  • Investigation of cellular and molecular aspects of the hemodynamic response of the brain.

Applications in nanotechnology:

  • Novel methods of plasmonic phenomena observation in nanostructures with CCHM.



Published paper "Quantitative phase imaging unravels new insight…

New paper "Quantitative phase imaging unravels new insight into dynamics of mesenchymal and amoeboid cancer cell… Read more »


​​2nd international meeting - PHASE IN BRNO 2018: Dry-Mass…

Date: 22-24 October, 2018 Venue: CEITEC BUT, Purkynova 656/123, Brno, Czech Republic The meeting will… Read more »


Published paper "Dual-polarization interference microscopy for…

New paper "Dual-polarization interference microscopy for advanced quantification of phase associated with the image… Read more »